PHARMACOGNOSTIC CHARACTERISTIC OF KAEMPFERIA GALANGA RHIZOME DRIED BY OVEN AND COMBINATION METHODS
DOI:
https://doi.org/10.22159/ijap.2022.v14s4.PP38%20Keywords:
Combination drying, Kampferia galanga, Pharmacognostic characteristic, Oven dyingAbstract
Objective: The research objective was to determine the effect of the drying process on the pharmacognostic characteristic of dried Kampferia galanga produced in the Post-Harvest Processing Center of Medicinal Plants facility.
Methods: The drying methods were oven-based drying in 80 °C temperature and a combination-based drying process, which included greenhouse drying for 6-8 h and transfered to 80 °C oven. The pharmacognostic characteristic of products were evaluated based on Indonesian Herbal Pharmacopeia standard, which included macroscopic and microscopic evaluation, thin-layer chromatography, water and ethanol soluble content, total ash and acid-insoluble ash content, volatile oil content, ethyl para-methoxycinnamate content, total plate count, and total yeast and mold count.
Results: The result showed dried K. galanga from both drying methods met the quality standard. Interestingly, the combination-based methods possed 6-7 h quicker in drying time compared to oven-based methods despite lower temperatures was used at the greenhouse.
Conclusion: It can be concluded that both methods could retain the quality of K. galanga rhizome.
Downloads
References
World Health Organization, WHO expert committee on specifications for pharmaceutical preparations. 5th sec report of the WHO Expert Committee on Specifications for Pharmaceutical Preparations. Available from: https://apps.who.int/iris/handle/10665/272452.
World Health Organization. Quality control methods for herbal materials. Geneva, Switzerland: World Health Organization; 2011.
Silalahi M, Nisyawati, Walujo EB, Supriatna J, Mangunwardoyo W. The local knowledge of medicinal plants trader and diversity of medicinal plants in the Kabanjahe traditional market, North Sumatra, Indonesia. J Ethnopharmacol. 2015;175:432-43. doi: 10.1016/j.jep.2015.09.009. PMID 26435224.
Noro T, Miyase T, Kuroyanagi M, Ueno A, Fukushima S. Monoamine oxidase inhibitor from the rhizomes of Kaempferia galanga L. Chem Pharm Bull (Tokyo). 1983;31(8):2708-11. doi: 10.1248/cpb.31.2708, PMID 6652816.
Kiuchi F, Nakamura N, Tsuda Y, Kondo K, Yoshimura H. Studies on crude drugs effective on visceral larva migrans. II. Larvicidal principles in kaempferiae rhizoma. Chem Pharm Bull (Tokyo). 1988;36(1):412-5. doi: 10.1248/cpb.36.412. PMID 3378302.
Choochote W, Kanjanapothi D, Panthanga A, Taesotikul T, Jitpakdi A, Chaithong U. Larvicidal and repellent effects of Kaempferia galanga. South East Asian J Trap Med Public Health. 1999;30:470-6.
Kosuge T, Yokota M, Sugiyama K, Saito M, Iwata Y, Nakura M. Studies on anticancer principles in Chinese medicines. II. Cytotoxic principles in Biota orientalis (L.) Endl and Kaempferia galanga L. Chem Pharm Bull (Tokyo). 1985;33(12):5565-67. doi: 10.1248/cpb.33.5565, PMID 3833396.
Xue Y, Chen H. Study on the anticarcinogenic effect of three compounds of Kaempferia galanga L. Xei Shen Yan Jiu. 2002;31(4):247-48, 251.
Jagadish PC, Raghu CH, Vinod KS, Latha KP. Potent selective cytotoxic activity of Kaempferia galanga rhizome against cancer cell cultures. Int J Pharm Biol Sci. 2010;1:1-5.
Chithra M, Martin KP, Sunandakumari C, Madhusoodanan PV. Protocol for rapid propagation, and to overcome delayed rhizome formation in field established in vitro derived plantlets of Kaempferia galanga L. Scientia Horticulturae. 2005;104(1):113-20. doi: 10.1016/j.scienta.2004.08.014.
Indonesian Ministry of Health. Farmakope herbal Indonesia. 2nd ed. Jakarta, Indonesia: Indonesian Ministry of Health; 2017.
Indonesian Ministry of Health. Farmakope Indonesia. 5th ed. Jakarta, Indonesia: Indonesian Ministry of Health; 2014.
Badan Pengawas Obat dan Makanan. Peraturan BPOM Tahun 2019 tentang Persyaratan Mutu Obat Tradisional. Vol. 32. Jakarta, Indonesia: Badan Pengawas Obat dan Makanan; 2019.
Surekha D, Rajan VST, Kumar NA, Parameswari SA, Chetty CM. A review on role of quality control and quality assurance system in regulation of herbal drugs. Int J Res Phyochem Pharmacol. 2016;6(2):32-40.
Raina AP, Abraham Z. Chemical profiling of essential oil of Kaempferia galanga L. Germplasm from India. J Essent Oil Res. 2016;28(1):29-34. doi: 10.1080/10412905.2015.1077165.
Srivastava N, Ranjana, Singh S, Gupta AC, Shanker K, Bawankule DU. Aromatic ginger (Kaempferia galanga L.) extracts with ameliorative and protective potential as a functional food, beyond its flavor and nutritional benefits. Toxicol Rep. 2019;6:521-8. doi: 10.1016/j.toxrep.2019.05.014. PMID 31431884.
Ichwan SJA, Husin A, Suriyah WA, Lestari W, Omar MN, Kasmuri AR. Anti-neoplastic potential of ethyl-p-methoxycinnamate of Kaempferia galanga on oral cancer cell lines. Materials Today: Proceeding. 2019;16(4):2115-21. doi: 10.1016/j.matpr.2019.06.100.
Hudha MI, Daryono ED, Muyassaroh M. Minyak ken cur dari rimpang ken cur dengan variabel jumlah pelarut dan waktu maserasi. J Tekn Kimia. 2013;8(1):1-7.
Gandjar Rohman A. Analisis obat secara spektrofotometri dan kromatografi. Yogyakarta, Indonesia: Pustaka Pelajar; 2012.
Zamir R, Hosen A, Ullah MO, Nahar N. Microbial and heavy metal contaminant of antidiabetic herbal preparations formulated in Bangladesh. Evid Based Complement Alternat Med. 2015;2015:243593. doi: 10.1155/2015/243593, PMID 26587044.
Published
How to Cite
Issue
Section
Copyright (c) 2022 RADEN BAYU INDRADI, YASMIWAR SUSILAWATI, ZELIKA MEGA RAMADHANIA, ASRI SAVITRI, SOLEH SOLEH, ADE ZUHROTUN, YOPPI ISKANDAR
This work is licensed under a Creative Commons Attribution 4.0 International License.
