ANTIOXIDANT ACTIVITIES AND PHYTOCHEMICAL SCREENING OF ETHANOL EXTRACT FROM SURIAN LEAVES (TOONA SINENSIS)

Authors

  • UCE LESTARI Doctoral Study Program, Faculty of Pharmacy, Universitas Padjadjaran, Sumedang-45363, West Java, Indonesia. Department of Pharmacy, Faculty of Medicine and Health Sciences, University of Jambi, Jambi, Indonesia
  • MUHAIMIN MUHAIMIN Department of Pharmaceutical Biology, Faculty of Pharmacy, Universitas Padjadjaran, Jawa Barat. Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmacy, Universitas Padjadjaran, Sumedang-45363, West Java, Indonesia
  • ANIS YOHANA CHAERUNISAA Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmacy, Universitas Padjadjaran, Sumedang-45363, West Java, Indonesia
  • WAWAN SUJARWO Ethnobotany Research Group, Research Center for Ecology and Ethnobiology, National Research and Innovation Agency (BRIN), Jakarta

DOI:

https://doi.org/10.22159/ijap.2023.v15s2.07

Keywords:

Antioxidants, Surian leaves, IC50

Abstract

Objective: The objective of the present study is to determine antioxidant activities and phytochemical screening of ethanol extract from surian leaves (Toona sinensis).

Methods: This study evaluated the antioxidant activity and conducted phytochemical screening of ethanol extracts obtained from surian leaves. Phytochemical screening was performed using qualitative Thin-Layer Chromatography (TLC), and antioxidant activity was assessed using the DPPH method.

Results: The results revealed the presence of polyphenolic compounds (153.10±0.310 mg/g), tannins, flavonoids (33.19±0.890 mg/g), monoterpenoids, quinones, and saponins with Rf values of 0.607±0.019 (flavonoids) and 0.958±0.019 (terpenoids) 0.513±0.038 (steroids) 0.418±0.019 (phenolics). The antioxidant activity test of the ethanol extract from Surian leaves yielded an IC50 value of 12.351±0.092 ppm, which closely matches the IC50 value of the reference vitamin C (7.805±0.686 ppm).

Conclusion: In conclusion, based on research methods, the ethanol extract of surian leaves contains flavonoid and phenolic compounds which show strong antioxidant activity.

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Published

18-12-2023

How to Cite

LESTARI, U., MUHAIMIN, M., CHAERUNISAA, A. Y., & SUJARWO, W. (2023). ANTIOXIDANT ACTIVITIES AND PHYTOCHEMICAL SCREENING OF ETHANOL EXTRACT FROM SURIAN LEAVES (TOONA SINENSIS). International Journal of Applied Pharmaceutics, 15(2), 37–43. https://doi.org/10.22159/ijap.2023.v15s2.07

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