CURRENT PERSPECTIVES ON USING NANOPARTICLES FOR DIABETES MANAGEMENT

Abstract

If ignored, diabetes mellitus, a chronic metabolic disease marked by high levels of blood glucose, can have serious negative effects on one's health. The efficacy, safety, and patient compliance of traditional treatment approaches, like insulin injections and oral medications, are frequently hampered. Nanoparticle-based methods have shown promise in recent years as improved diabetes management techniques. Enhanced bioavailability, prolonged therapeutic effects, and targeted drug delivery are just a few of the special benefits that come with using nanoparticles. An overview of current perspectives on using nanoparticles for diabetes control is given in this review. The properties, production processes, and potential uses of several types of nanoparticles, such as polymeric, lipid-based, and inorganic nanoparticles, in the management of diabetes, are covered. These nanoparticles allow for the precise delivery of therapeutic agents, such as insulin or anti-diabetic medications, to specific target tissues, like the liver or pancreas. It discusses how inorganic NPs, polymeric nanoparticles (PNPs), and lipid-based nanoparticles (LNPs) contribute to improved drug solubility, targeted delivery, and controlled release. Several methods for synthesizing polymeric nanoparticles are described. It also discusses the potential anti-inflammatory and antioxidant properties of some nanoparticles and how crucial they are to lowering diabetes-related issues. By incorporating the most recent research, this review offers a comprehensive summary of the current developments in the use of nanoparticles for diabetes control, paving the way for enhanced therapeutic outcomes and tailored interventions.